Abstract Background Germline BRCA2 mutation is associated with an aggressive prostate cancer phenotype and indicates higher risk for hereditary cancer.Recently, numerous studies have attempted to identify the genomic landscape of prostate cancer to better understand the genomic drivers of this disease and look for the molecular targets to guide tre
Photodynamic therapy as an up-to-date medical technology for the treatment of vulgar acne
Background.Acne occurs in at least 85 % of male and female teenagers, often lasts a long time, with relapses in the 3rd and 4th decades of life.Since 2000, the technology of photodynamic therapy (PDT) has Crimpers been actively used in many countries.Over the past two years, numerous important studies on the effectiveness of PDT for the treatment o
A real-time prediction method for ship heave motion using NARX neural network
Objectives Predicting heave motion is helpful for improving the performance of the heave compensator and reducing the disturbance of waves on operating equipment.To improve the accuracy and stability of the heave prediction model, a real-time prediction method for ship heave motion is proposed in this paper.Methods Based on the Nonlinear Autoregres
Bothrops jararaca venom metalloproteinases are essential for coagulopathy and increase plasma tissue factor levels during envenomation.
BACKGROUND/AIMS:Bleeding tendency, coagulopathy and platelet disorders are recurrent manifestations in snakebites occurring worldwide.We reasoned that by damaging tissues and/or activating cells at the site of the bite and systemically, snake venom toxins might release or decrypt tissue factor (TF), resulting in activation of blood coagulation and
Electrochemiluminescence Study of Europium (III) Complex with Coumarin3-Carboxylic Acid
The europium (III) complex of coumarin-3-carboxylic acid (C3CA) has been prepared and characterized on the basis of elemental analysis, IR, and emission (photoluminescence and electrochemiluminescence) spectroscopy.The synthesised complex Chest having a formula Eu(C3CA)2(NO3)(H2O)2 was photophysically characterized in solution and in the solid stat